TY - JOUR T1 - PRogressive lenticular degeneration associated with cirrhosis of the liver (wilson's disease) AU - HOWARD CP, ROYCE CE Y1 - 1919/11/01 N1 - 10.1001/archinte.1919.00090280028003 JO - Archives of Internal Medicine SP - 497 EP - 508 VL - 24 IS - 5 N2 - Our excuse for presenting before the association a case report with its postmortem findings is the rarity of the condition both in America and in Europe. Since Wilson first described the disease in 1912, not more than twenty-six cases have been reported, of which thirteen were observed by various American neurologists. The clinical history of our case was as follows:REPORT OF CASE  H. B., white, male, aged 22 years, farmer by occupation, was referred by Dr. C. M. Wray of Iowa Falls, and admitted to the medical clinic, Dec. 11, 1916.Entrance Complaints.  —Painful cramps in the toes of the right foot and edema of both lower extremities.Family History.  —Father died at 45 years of age from tuberculosis of the lungs. Mother is alive and well. There are three brothers, two about patient's age and the third 5 years old, all living and well. One brother died in SN - 0730-188X M3 - doi: 10.1001/archinte.1919.00090280028003 UR - http://dx.doi.org/10.1001/archinte.1919.00090280028003 ER -