TY - JOUR T1 - SCreen detection has both winners and losers AU - Keen JD, Keen J Y1 - 2012/03/12 N1 - 10.1001/archinternmed.2011.1885 JO - Archives of Internal Medicine SP - 447 EP - 447 VL - 172 IS - 5 N2 - Dr Welch is a pioneer in presenting the benefits and harms of screening to both clinicians and the public. However, Keen and Keen1- 2 were the first to devise the method to calculate the life-saving proportion (LSP) of screen-detected breast cancers, using matched 15-year periods. The follow-up analysis promoting screening mammography insight used 10-year periods.3 The higher percentage of screen-detected cancers (61%-64% vs 50%-56%) in the article by Welch and Frankel4 makes our estimates higher, while the mixed 20-year/10-year death/diagnosis risk makes our estimates lower. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2011.1885 UR - http://dx.doi.org/10.1001/archinternmed.2011.1885 ER -