TY  - JOUR
T1  - Young-onset colorectal cancer: Is it time to pay attention?
AU  - You Y, Xing Y, Feig BW, Chang GJ, Cormier JN
Y1  - 2012/02/13
N1  - 10.1001/archinternmed.2011.602
JO  - Archives of Internal Medicine
SP  - 287
EP  - 289
VL  - 172
IS  - 3
N2  - 
The 2010 Annual Report to the Nation on Cancer celebrated a steady decline in the incidence of colorectal cancer (CRC).1 This progress has been largely attributed to CRC screening, recommended for adults 50 years or older since 1996.2 In sharp contrast to overall trends, the incidence of CRC appears to be increasing among adults younger than 50 years,1,3 a group for whom average-risk screening is not routine. Particularly concerning is a trend toward advanced-stage CRCs,1,3 suggesting a potential role for increased clinical vigilance and more prompt evaluation of symptomatic patients. To raise clinical awareness and facilitate recognition, we undertook a cohort study to (1) examine incidence trends; (2) define the distinct clinicopathologic manifestations of young-onset CRC; and (3) identify risk factors for advanced-stage disease.

SN  - 0003-9926
M3  - doi: 10.1001/archinternmed.2011.602
UR  - http://dx.doi.org/10.1001/archinternmed.2011.602
ER  -