TY - JOUR T1 - A question of the clinical relevance of determining thrombomodulin level while receiving anticoagulant therapy AU - Nguyen C, Chan G, Su M Y1 - 2009/11/23 N1 - 10.1001/archinternmed.2009.422 JO - Archives of Internal Medicine SP - 2031 EP - 2031 VL - 169 IS - 21 N2 - We would like to thank Lind et al1 for their study on thrombomodulin as a marker for bleeding complications during warfarin treatment. This longitudinal cohort study demonstrates that patients who have high levels of soluble thrombomodulin (sTM) and are receiving long-term vitamin K antagonist therapy appear to be at higher risk of clinically relevant and major bleeding complications. If validated, such a laboratory test would be of great importance and clinical utility in assessing the risk of long-term vitamin K antagonist therapy. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2009.422 UR - http://dx.doi.org/10.1001/archinternmed.2009.422 ER -