TY - JOUR T1 - IS red blood cell distribution width a marker of overall membrane integrity? AU - Goldstein MR, Mascitelli L, Pezzetta F Y1 - 2009/09/12 N1 - 10.1001/archinternmed.2009.275 JO - Archives of Internal Medicine SP - 1539 EP - 1540 VL - 169 IS - 16 N2 - Cholesterol, a major and essential structural component of all cell membranes, modulates the functions of membrane proteins and participates in membrane trafficking and signaling processes.2 As a result, alterations in membrane cholesterol content might adversely affect the functions of many organ systems. Interestingly, the quintile of subjects exhibiting the highest baseline RDW and subsequent highest mortality had the lowest baseline prevalence of hypercholesterolemia.1 SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2009.275 UR - http://dx.doi.org/10.1001/archinternmed.2009.275 ER -