TY - JOUR T1 - VItamin d level, respiratory tract infections, and controlled trials—reply AU - Ginde AA, Mansbach JM, Camargo CA, Jr Y1 - 2009/08/10 N1 - 10.1001/archinternmed.2009.247 JO - Archives of Internal Medicine SP - 1443 EP - 1444 VL - 169 IS - 15 N2 - We thank Dr Hemilä for this correspondence. The Cochrane review by Douglas et al1 supported our statement that vitamin C has a limited role in prevention and treatment of colds and concluded that the prophylactic or therapeutic use of vitamin C does not reduce the incidence or severity of colds. There was a modest reduction (approximately 12 hours) in duration of colds with prophylactic but not therapeutic use of vitamin C, but as those authors conclude, “there seems no justification for routine mega-dose vitamin C supplementation in the normal population” and “therapeutic supplementation has not been shown to be beneficial.”1 SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2009.247 UR - http://dx.doi.org/10.1001/archinternmed.2009.247 ER -