TY - JOUR T1 - Percutaneous coronary intervention for persistent occlusion of the infarct-related artery: An expanded view of the evidence AU - Appleton D, Abbate A, Biondi-Zoccai G Y1 - 2011/11/28 N1 - 10.1001/archinternmed.2011.551 JO - Archives of Internal Medicine SP - 1962 EP - 1963 VL - 171 IS - 21 N2 - Abbate et al3 performed a meta-analysis of 10 randomized trials comparing late PCI with medical therapy (including the OAT) in the setting of acute MI and showed an overall survival benefit favoring PCI. There was also a significant improvement in left ventricular ejection fraction and reduced cardiac volumes. Appleton and colleagues4 restricted their meta-analysis to only include trials with persistent total occlusion of the IRA, showing that PCI was associated with a statistically significant improvement in LVEF and cardiac remodeling. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2011.551 UR - http://dx.doi.org/10.1001/archinternmed.2011.551 ER -