TY - JOUR T1 - ACid suppressive therapy in noncritically ill patients—reply AU - Herzig SJ, Marcantonio ER Y1 - 2011/11/14 N1 - 10.1001/archinternmed.2011.514 JO - Archives of Internal Medicine SP - 1862 EP - 1864 VL - 171 IS - 20 N2 - We thank Barletta and El-Ibiary for their insightful comments. We wholeheartedly agree regarding the importance of attempting to identify subgroups of hospitalized, noncritically ill patients with heightened risk for nosocomial GI bleeding to determine if risk is high enough to warrant routine prophylaxis with acid-suppressive medication. Such analyses in critically ill patients were instrumental in identifying high- and low-risk subgroups of patients with numbers needed to treat of 30 and 900, respectively.1 We are currently completing such analyses in our large cohort of hospitalized, noncritically ill patients and hope to shed light on this issue in the future. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2011.514 UR - http://dx.doi.org/10.1001/archinternmed.2011.514 ER -