TY - JOUR T1 - RIsk of heart failure with human immunodeficiency virus is greater than hypertension?—reply AU - Butt AA, Justice AC, Freiberg MS Y1 - 2011/10/24 N1 - 10.1001/archinternmed.2011.560 JO - Archives of Internal Medicine SP - 1773 EP - 1774 VL - 171 IS - 19 N2 - We thank de Melo Neto et al for their insightful comments about our article.1 We agree that using ICD-9 codes can potentially introduce a bias in any analysis using such data. We have previously validated hypertension ICD-9 codes against structured medical chart review as the gold standard.2 Among HIV-infected persons enrolled in the 3-site Veterans Aging Cohort Study, the prevalence of hypertension by ICD-9 codes and medical chart reviews was 28% and 32% respectively, with an agreement of 85.2% and a κ value of 0.65. Hence, there may have been a slight underreporting of hypertension in the HIV-infected group. We are currently evaluating whether diagnosis of hypertension differs by HIV status using actual blood pressure measurement. For diabetes, we used a combination of laboratory measurements, use of insulin and oral hypoglycemic medications, and ICD-9 codes, as used in several previous studies.3- 4 SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2011.560 UR - http://dx.doi.org/10.1001/archinternmed.2011.560 ER -