TY - JOUR T1 - CArdiovascular device technology and health care cost—reply AU - Redberg RF Y1 - 2011/10/10 N1 - 10.1001/archinternmed.2011.465 JO - Archives of Internal Medicine SP - 1689 EP - 1689 VL - 171 IS - 18 N2 - I agree with Dr Dean's statement that the “application of therapy should be based on the evidence.” That is why it is disappointing that he refers to the “life-saving properties” of DESs without offering support for this statement. Indeed, significant mortality benefits have not been seen with DESs.1 The end point used in almost all large, high-quality randomized controlled trials on this subject is a composite outcome, largely driven by decreased need for revascularization. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2011.465 UR - http://dx.doi.org/10.1001/archinternmed.2011.465 ER -