TY - JOUR T1 - OUtcome-blinded peer review—reply AU - Emerson GB, Warme WJ, Wolf FM, Heckman JD, Brand RA, Leopold SS Y1 - 2011/07/11 N1 - 10.1001/archinternmed.2011.290 JO - Archives of Internal Medicine SP - 1213 EP - 1214 VL - 171 IS - 13 N2 - It is not clear to us that raising awareness of a natural human tendency (to be drawn to a finding over an absence of one), or that reminding reviewers and editors that articles should be judged on methodological rigor rather than by the direction of the outcomes, will result in any sort of counteracting bias. Similarly, finding the means to publish high-quality, no-difference or “negative” studies, whether in print, in electronic editions, or in searchable online appendixes, seems to offer little downside, while providing a mechanism for no-difference studies to be identified by meta-analyses, decision analyses, and other forms of synthetic research. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2011.290 UR - http://dx.doi.org/10.1001/archinternmed.2011.290 ER -