RT Journal
A1 ANDERSON JF, ROSENAU MJ
T1 ANaphylaxis
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1909
FD June 1
VO III
IS 5
SP 519
OP 568
DO 10.1001/archinte.1909.00050160152012
UL http://dx.doi.org/10.1001/archinte.1909.00050160152012
AB Anaphylaxis (ana, against, and phylax, guard, or phylaxis, protection), also called hypersusceptibility, supersensitiveness, is a condition of unusual or exaggerated susceptibility of the organism to foreign substances. The word "anaphylaxis" was introduced by Richet to describe a contrary condition to prophylaxis. As we now regard the phenomenon, the word is a misnomer, for we look upon the condition of hypersusceptibility as a distinct benefit and advantage to the organism. In fact, protection against a large class of infections depends on an altered power of reaction, i. e., hypersusceptibility or anaphylaxis.This state may be congenital or acquired, and is specific in nature. The condition of anaphylaxis may be brought about by the introduction of any strange protein into the body. Hypersusceptibility to proteins that are non-poisonous in themselves may readily be induced in certain animals.An animal may be in a condition of hypersusceptibility and