RT Journal
A1 EPSTEIN AA, OTTENBERG RR
T1 A method for hemolysis and agglutination tests
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1909
FD May 1
VO III
IS 4
SP 286
OP 288
DO 10.1001/archinte.1909.00050150011002
UL http://dx.doi.org/10.1001/archinte.1909.00050150011002
AB The established methods of testing for agglutination and hemolysis have been developed chiefly in animal experimentation, and their application to work with human blood is encumbered with certain hindrances. In all serum reactions there is great need for control tests. The quantity of blood which it is necessary to take from patients for these tests limits the work to a certain extent and, therefore, interferes with the drawing of definite conclusions.To overcome these obstacles we have developed a method whereby it is possible to perform a large number of tests with a very small amount of blood. In principle the method is identical with that now used by all investigators in this field. In details of technic it is an application of the method used by Wright in his work with opsonins. It has for its main object the reduction to a minimum of the amount of