RT Journal
A1 Koch CA, Archer TP, Kraut EH
T1 MYocardial ischemia in a patient with chronic refractory idiopathic thrombocytopenic purpura
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1997
FD December 8
VO 157
IS 22
SP 2668
OP 2668
DO 10.1001/archinte.1997.00440430150028
UL http://dx.doi.org/10.1001/archinte.1997.00440430150028
AB The importance of platelets in the development of ischemic coronary syndromes has been documented in animal models. The use of antiplatelet agents in coronary artery disease is well established. Theoretically, qualitative and quantitative depression of platelet function should prevent the development of arterial occlusion. Myocardial ischemia occurring with chronic idiopathic thrombocytopenia has been rarely documented.1-3 We describe a patient with non—Q-wave myocardial infarction (MI) and chronic refractory idiopathic thrombocytopenic purpura (ITP).Report of a Case. 
    A 52-year-old premenopausal woman presented to our institution with new-onset unstable angina. Her medical history included chronic refractory ITP diagnosed at age 39 years and treated by splenectomy, prednisone, danazol, and intermittent intravenous immunoglobulin. After age 39 years, our patient also suffered from diabetes mellitus, hypertension, and hepatitis C. She was a nonsmoker and not taking aspirin. Her blood pressure was 180/100 mm Hg, and pulse, 90 bpm. The results of a physical examination were