RT Journal
A1 Grossman E, Carroll J, Rosenthal T
T1 LEft ventricular hypertrophy in diabetic patients-reply
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1993
FD January 11
VO 153
IS 1
SP 126
OP 126
DO 10.1001/archinte.1993.00410010143021
UL http://dx.doi.org/10.1001/archinte.1993.00410010143021
AB We welcome the comments by Leibowitz and Bursztyn raising an additional possible explanation for the accelerated development of left ventricular hypertrophy in non—insulin-dependent diabetes mellitus. We agree with these authors that ambulatory blood pressure monitoring is more closely related to left ventricular mass than are casual blood pressure measurements.1 However, even ambulatory blood pressure monitoring has been only weakly related to echocardiographic left ventricular mass,1 indicating other nonhemodynamic causes for the development of left ventricular hypertrophy. In a substantial number of our patients with 24-hour blood pressure monitoring, there was no significant difference in the nocturnal decline of blood pressure level between the diabetic and the nondiabetic patients. Thus, lack of nocturnal decline in the blood pressure level is difficult to integrate with the accelerated development of left ventricular hypertrophy in diabetic patients. Moreover, Barbagallo et al2 recently have suggested that ambient blood glucose level, independent of