RT Journal A1 KAPLAN NM T1 HOw bad are diuretic-induced hypokalemia and hypercholesterolemia? JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1989 FD December 1 VO 149 IS 12 SP 2649 OP 2649 DO 10.1001/archinte.1989.00390120021005 UL http://dx.doi.org/10.1001/archinte.1989.00390120021005 AB For those who work in the hypertension field and for all practitioners who deal with hypertensive patients, Ed Freis is a hero, responsible for the first documentation that the treatment of moderate hypertension would save lives1 and for a steady stream of useful data over the past 20 years as the principal investigator of the Veterans Administration Cooperative Study Group. Moreover, Dr Freis was one of the first voices to be heard advising caution regarding the overtreatment of mild hypertension,2 despite his having been the one largely given credit for the current enthusiasm toward "early and aggressive therapy." Knowing how careful and thoughtful he is, I am sure he must have viewed the subsequent trend toward overly aggressive therapy as a problem he simply had to stand up to.Therefore, I reviewed Dr Freis' article published in this issue of the Archives3as one who both admires