RT Journal
A1 Jackson JA, Waxman J, Spiekerman A
T1 PRostatic complications of testosterone replacement therapy
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1989
FD October 1
VO 149
IS 10
SP 2365
OP 2366
DO 10.1001/archinte.1989.00390100157033
UL http://dx.doi.org/10.1001/archinte.1989.00390100157033
AB • The prostatic complications of testosterone replacement therapy have received little clinical attention. We describe three hypogonadal men who had prostatic disease (adenocarcinoma in two) detected in relation to such therapy. Literature review suggests that surveillance for early prostate cancer is appropriate during replacement therapy in men over the age of 50 years. We discuss the selective use of digital rectal examination, transrectal sonography, directed prostate biopsy, and prostate-specific antigen determinations before therapy and in subsequent follow-up in this age group of men during androgen replacement.(Arch Intern Med. 1989;149:2365-2366)