RT Journal
A1 Brooks RG
T1 PRospective study of candida endophthalmitis in hospitalized patients with candidemia
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1989
FD October 1
VO 149
IS 10
SP 2226
OP 2228
DO 10.1001/archinte.1989.00390100056014
UL http://dx.doi.org/10.1001/archinte.1989.00390100056014
AB • To determine the frequency of endogenous Candida endophthalmitis in patients with candidemia, we prospectively evaluated 32 inpatients with fungemia by weekly indirect ophthalmoscopic examinations. Chorioretinitis compatible with Candida infection was found in 9 (28%) patients. Patient age, sex, underlying diseases, or hospital-acquired factors, such as presence of central venous or Foley catheters, bacteremia, use of multiple antibiotics, hyperalimentation, or surgery, did not distinguish between groups. Groups were also similar in number of sites colonized with yeast and species of Candida recovered. Patients with endophthalmitis tended to have more blood cultures positive for Candida (mean, 4.3) than the patients without endophthalmitis (mean, 2.8), but this trend did not reach statistical significance. Based on these results, we recommend periodic ophthalmoscopic examinations in all patients with documented candidemia.(Arch Intern Med. 1989;149:2226-2228)