RT Journal
A1 KING JW, TODD JR, WEST BC
T1 WEgener's granulomatosis
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1989
FD July 1
VO 149
IS 7
SP 1695
OP 1698
DO 10.1001/archinte.1989.00390070193038
UL http://dx.doi.org/10.1001/archinte.1989.00390070193038
AB To the Editor.—We were intrigued and gratified to read another article on Wegener's granulomatosis in which a favorable response to treatment with sulfamethoxazole and trimethoprim was documented.1 That patient is unusual among the small number of similar reports for not having received cyclophosphamide treatment. Since the text and Fig 11 do not permit their assessment, we would be interested in learning the extent of the vasculitis in the biopsy specimen, and whether or not acid-fast, periodic acid–Schiff, and various silver stains were performed.Elsewhere, we documented a complete and sustained remission in Wegener's granulomatosis with sulfamethoxazole and trimethoprim treatment.2 Because of the limited reference to our observations in the recent article, which reads "... a single case was reported of a patient with Wegener's granulomatosis treated unsuccessfully with steroids and cyclophosphamide who seemed to respond coincidentally with the use of sulfamethoxazole-trimethoprim,1" please allow us to reiterate