RT Journal A1 YORK E T1 EXercise in controlling serum lipid levels JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1989 FD January 1 VO 149 IS 1 SP 223 OP 223 DO 10.1001/archinte.1989.00390010183029 UL http://dx.doi.org/10.1001/archinte.1989.00390010183029 AB To the Editor.—An editorial1 and article2 appearing in the May issue of the Archives discussed the role of diet in controlling cholesterol levels. Although diet and pharmacologic manipulation may help in lowering serum lipid levels, nevertheless, neither the author of the editorial nor the authors of the article discuss the role of exercise. Many physicians, epidemiologists, and informed members of the public are aware that aerobic activity, when quantified as to duration, frequency, and intensity, may facilitate weight control as well as controlling serum lipid levels.3,4Over a hundred years ago, an eminent Bostonian, Oliver Wendell Holmes, MD,5 remarked "I firmly believe that if the whole materia medica as now used could be sunk to the bottom of the sea, it would be all the better for mankind—and all the worse for the fishes." His comment should remind all of us to be cautious about