RT Journal
A1 Gill PS, Levine AM, Meyer PR, et al
T1 Human t-cell lymphotropic virus type iii associated disorders: The spectrum in the heterosexual population
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1986
FD August 1
VO 146
IS 8
SP 1501
OP 1504
DO 10.1001/archinte.1986.00360200051008
UL http://dx.doi.org/10.1001/archinte.1986.00360200051008
AB • Eleven heterosexual patients (nine women, two men) without classic risk factors for development of acquired immunodeficiency syndrome (AIDS) were seen between March 1983, and April 1985, and diagnosed as having AIDS (four), persistent, generalized lymphadenopathy (PGL) (four), or asymptomatic human T-cell lymphotropic virus type III (HTLV-III) carrier state (three). The clinical presentations and course of those with AIDS or PGL were similar to those reported in homosexual men with AIDS or PGL, with reversed T4/T8 ratio, and the presence of antibody to HTLV-III. Asymptomatic carriers had normal T4/T8 ratios, had an absence of HTLV-III antibodies, but had HTLV-III virus cultured from blood. We conclude that the heterosexual population, with or without history of sexual exposure to individuals at risk for AIDS, may develop a wide range of clinical manifestations secondary to HTLV-III, varying from AIDS to the asymptomatic carrier state.(Arch Intern Med 1986;146:1501-1504)