RT Journal A1 Gotfried M, Jutrin H, Ravid M T1 BEhçet's disease preceded by fever of unknown origin JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1985 FD July 1 VO 145 IS 7 SP 1329 OP 1329 DO 10.1001/archinte.1985.00360070211038 UL http://dx.doi.org/10.1001/archinte.1985.00360070211038 AB To the Editor.  — Behçet's disease, first described in 1937, is best defined as a clinical triad of recurrent ocular inflammation, oral and vaginal ulcers, and a cutaneous hyperreactivity to minor trauma.1 A myriad of additional features was described in individual patients, including arthritis, colitis, various forms of vasculitis, venous thrombosis, and amyloidosis. Fever may accompany other acute manifestations during the course of the disease2,3; however, to the best of our knowledge, it has never been described as a sole manifestation preceding the other phenomena.Report of a Case.  —A 27-year-old woman was admitted for investigation of fever of eight weeks' duration. Physical examination was notable only for a palpable spleen, 5 cm below the costal margin. Blood pressure was 120/80 mm Hg; pulse, 95 beats per minute and regular; and temperature, 38.5 °C. The erythrocyte sedimentation rate was 30 mm/hr (Westergren). The hemoglobin level was 12.6 mg/dL