RT Journal
A1 Aronson AJ, Ordoñez NG, Diddie KR, Ernest J
T1 IMmune-complex deposition in the eye in systemic lupus erythematosus
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1979
FD November 1
VO 139
IS 11
SP 1312
OP 1313
DO 10.1001/archinte.1979.03630480084026
UL http://dx.doi.org/10.1001/archinte.1979.03630480084026
AB A patient with systemic lupus erythematosus (SLE) and lupus retinopathy showed resolution of subretinal edema documented with fluorescein angiography. Subsequently at autopsy, immunofluorescence studies disclosed ocular deposition of immunoglobulins in the vascular layer of choroid capillaries and basement membranes of ciliary processes and bulbar conjunctivas. To our knowledge, these findings represent the first reported documentation of probable immune-complex ocular vasculitis in lupus retinopathy using immunofluorescent techniques, and they support the hypothesis that lupus retinopathy is caused by immune complex deposition as are other manifestations of SLE.(Arch Intern Med 139:1312-1313, 1979)