RT Journal A1 Esposito AL, Gleckman RA T1 A diagnostic approach to the adult with fever of unknown origin JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1979 FD May 1 VO 139 IS 5 SP 575 OP 579 DO 10.1001/archinte.1979.03630420061019 UL http://dx.doi.org/10.1001/archinte.1979.03630420061019 AB The evaluation of the condition of a patient with fever of unknown origin requires a knowledge of those disorders that produce this syndrome, an awareness of the potential significance of subtle findings in the history and physical examination, and an appreciation of the value in this clinical setting of specific diagnostic procedures. In this report, we review these aspects of fever of unknown origin and outline a diagnostic approach to the persistently febrile patient.(Arch Intern Med 139:575-579, 1979)