RT Journal A1 Presant C, Van Amburg AA, III, Avioli LV T1 BReast cancer JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1979 FD April 1 VO 139 IS 4 SP 452 OP 455 DO 10.1001/archinte.1979.03630410060019 UL http://dx.doi.org/10.1001/archinte.1979.03630410060019 AB Albert Van Amburg, MD, Chief Resident, Department of Medicine, The Jewish Hospital of St Louis: A 38-year-old premenopausal woman came to her private physician one month prior to hospitalization because of a mass in the right breast that was first noted two months prior to admission. Since the breast mass did not change in size during a complete menstrual cycle, she consulted her physician, who verified the presence of the mass, although the remainder of the physical examination findings were unremarkable. Mammograms suggested a malignant neoplasm because of small calcifications. Tissue obtained from an aspiration biopsy specimen of the lesion revealed a poorly differentiated adenocarcinoma, and the patient was hospitalized to initiate definitive therapy. A family history showed no evidence of carcinoma of the breast.On admission, the patient was observed to be a well-developed, well-nourished woman; blood pressure was 120/ 85 mm Hg, pulse rate was 78 beats per