RT Journal A1 Fisher ML, Parisi AF, Plotnick GD, DeFelice CE, Carliner NH, Fortuin NJ T1 ASsessment of severity of mitral stenosis by echocardiographic leaflet separation JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1979 FD April 1 VO 139 IS 4 SP 402 OP 406 DO 10.1001/archinte.1979.03630410012009 UL http://dx.doi.org/10.1001/archinte.1979.03630410012009 AB Mitral valve area (MVA) determined at cardiac catheterization was compared with M mode echocardiographic measurements in 44 patients with mitral stenosis and no substantial mitral regurgitation. Despite statistically significant correlations, measurements of anterior leaflet motion, including rate of diastolic closure (EF slope) were not useful in predicting severity of stenosis. In contrast, maximal diastolic separation of anterior and posterior leaflets (SEP) was more closely correlated with MVA and appears to have some predictive value. Narrow separation was associated with severe mitral stenosis. Wide separation was associated with relatively mild stenosis. Intermediate values in 16 of 44 patients (36%) were not of predictive value. Recognizing this limitation, measurement of maximal diastolic mitral leaflet separation from M mode echocardiograms is proposed as a simple and useful method for assessing severity of mitral stenosis.(Arch Intern Med 139:402-406, 1979)