RT Journal
A1 Prosser PR
T1 SIlent glands
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1979
FD February 1
VO 139
IS 2
SP 143
OP 144
DO 10.1001/archinte.1979.03630390009005
UL http://dx.doi.org/10.1001/archinte.1979.03630390009005
AB More than 15 years have passed since Rachel Carson alerted society to the potential hazards of chemical toxins that were accumulating in the soil, water, air, and food.1 Tremendous efforts on the part of government and industry have since been made toward detoxifying our environment. We are informed almost daily by the news media of developments in this area, and terms like "biodegradable," "ecology," "food chain," and "Environmental Protection Agency" have become part of everyday conversation.In light of the intense public awareness of this subject, it comes as something of a surprise that two distinct clinically significant endocrine deficiency syndromes that are directly attributable to exposure to commonly used pesticides have recently been described. The first, an insulin-deficient ketosis-prone form of diabetes mellitus accompanied by severe debilitating autonomic and peripheral polyneuropathy, has developed in virtually every person who has survived the ingestion of N-3-pyridylmethyl N′-p