RT Journal
A1 Muehrcke RC, Mandal AK, Gotoff SP, Isaacs EW, Volini FI
T1 THe clinical value of electron microscopy in renal disease
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1969
FD August 1
VO 124
IS 2
SP 170
OP 176
DO 10.1001/archinte.1969.00300180042008
UL http://dx.doi.org/10.1001/archinte.1969.00300180042008
AB Electron microscopy was performed on biopsy material from 179 patients with a variety of renal diseases. Electron microscopy established or significantly contributed to the diagnosis in 11 patients (6%) for whom light microscopic findings were normal or not definitive. It was most helpful in distinguishing renal vein thrombosis from other causes of membranous glomerulonephritis and in diagnosing tubular necrosis as the cause of acute renal failure and early diabetic glomerulosclerosis as the cause of asymptomatic proteinuria. It did not contribute to the diagnosis or management of the other renal diseases studied. Electron microscopy need not be performed as a routine procedure but it should be available for the occasional occurrence that otherwise defies diagnosis.