RT Journal
A1 Clapp JR, Robinson RR
T1 FUnctional characteristics of the transplanted kidney
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1969
FD May 1
VO 123
IS 5
SP 531
OP 536
DO 10.1001/archinte.1969.00300150049007
UL http://dx.doi.org/10.1001/archinte.1969.00300150049007
AB The transplanted kidney is capable of functioning normally for a relatively short period of time. The diuresis observed immediately after transplantation is due to decreased sodium reabsorption by the tubular epithelium. The cause of this impairment in sodium conservation is unknown. The injurious effects of trauma or ischemia or both must be considered as principal causes. A characteristic functional pattern is present during acute rejection; however, it is often difficult to distinguish function changes due to rejection from those due to other processes. The functional integrity of the transplanted kidney over long periods still remains speculative. Since this represents the most important criterion determining the future of renal transplantation, the need for continued assessment of function in renal allografts cannot be overemphasized.