RT Journal
A1 Lasagna LL
T1 A symposium on the evaluation of drug toxicity.
JF A.M.A. Archives of Internal Medicine
JO A.M.A. Archives of Internal Medicine
YR 1959
FD September 1
VO 104
IS 3
SP 508
OP 508
DO 10.1001/archinte.1959.00270090162024
UL http://dx.doi.org/10.1001/archinte.1959.00270090162024
AB This is a refreshing book. The formal presentations are for the most part unhackneyed, and the discussions are lively and thoughtful. I found the chapter by Hurst on sexual differences in toxicity of drugs and the one by Paget on the morphological evaluation of toxic action particularly stimulating. (Paget's "routine" histopathology looks fantastically complete, by comparison with American standards!) John Litchfield, the only American at the meeting, supplies another high spot with his thoughtful, off-beat analysis of "screening" for efficacy and toxicity.The volume is also pleasantly brief and can be held comfortably in one hand while one is lying in bed. It is recommended to pharmacologists and to those clinicians concerned with the investigation of new drugs.