RT Journal
A1 SHELINE GE, MILLER ER
T1 RAdioiodine therapy of hyperthyroidism
JF A.M.A. Archives of Internal Medicine
JO A.M.A. Archives of Internal Medicine
YR 1959
FD June 1
VO 103
IS 6
SP 924
OP 932
DO 10.1001/archinte.1959.00270060076010
UL http://dx.doi.org/10.1001/archinte.1959.00270060076010
AB Between September, 1945, and June, 1957, four hundred thirty-one patients with hyperthyroidism were treated with radioiodine at the University of California Medical Center. Although other large series of radioiodine-treated patients have been recorded,1-3 certain features regarding patient selection, duration of follow-up of the initial group of patients, incidence and time of hypothyroidism, and effect on exophthalmos suggested the present analysis.All patients with hyperthyroidism in whom definitive therapy with radioiodine was initiated between September, 1945, and June, 1957, are included in this study. Although at first patients with nodular goiter were not treated, after November, 1948, these have been accepted if a reasonably strong contraindication to thyroidectomy was present. Previous to 1953, patients of all ages were treated; patients under 40 years of age were treated since that time, however, only if there was a postsurgical recurrence or some factor contraindicating surgery or other form of therapy. Pregnancy or