RT Journal A1 CHRISTOFORIDIS AJ, BROWNING RH T1 PUlmonary tuberculosis associated with carcinoma of the lung JF A.M.A. Archives of Internal Medicine JO A.M.A. Archives of Internal Medicine YR 1959 FD February 1 VO 103 IS 2 SP 231 OP 238 DO 10.1001/archinte.1959.00270020059007 UL http://dx.doi.org/10.1001/archinte.1959.00270020059007 AB The principle of explaining all of the symptoms and findings of a patient as manifestations of the same disease entity is undoubtedly justified in the majority of cases. All physicians are familiar with exceptions to the rule, particularly in older patients in whom multiple diagnoses are not uncommon. Indeed, the early recognition of two major diseases in the same patient presents a real challenge, particularly if both major diseases involve the same organ.Coexistence of pulmonary tuberculosis and carcinoma of the lung is well known. In the cases reported a common feature is the late diagnosis of the neoplasm, with a paucity of survivals because the carcinoma is so far advanced that successful treatment cannot be applied. Moreover, many cases are recognized only at postmortem examination.Famous pathologists have tried to correlate the etiology of the two diseases in one way or another and sometimes in exactly opposite ways. Rokitansky