RT Journal A1 TOBIN JR, Jr., BAY EB, HUMPHREYS EM T1 Marfan's syndrome in the adult: Dissecting aneurysm of the aorta associated with arachnodactyly JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1947 FD October 1 VO 80 IS 4 SP 475 OP 490 DO 10.1001/archinte.1947.00220160054005 UL http://dx.doi.org/10.1001/archinte.1947.00220160054005 AB ARACHNODACTYLY (Marfan's syndrome) is a relatively rare familial symptom complex which is familiar to ophthalmologists, pediatricians and, to a lesser extent, orthopedic surgeons. It should be of interest to all physicians. We wish to summarize its important characteristics and emphasize the aortic lesions which may be associated with it.REVIEW OF THE LITERATURE  Although entitled dolichostenomelie by Marfan,1 Archard2 in 1902 emphasized the most characteristic feature of the syndrome, calling it arachnodactyly (spider fingers). In 1926 Piper and Irving-Jones,3 the first American physicians to record the condition, noted the frequency with which it is associated with congenital malformations of the heart. Futcher and Southworth4 in 1938 pointed out rheumatic endocarditis and pulmonary disorders as common medical complications. In 1943 Baer, Taussig and Oppenheimer5 reported 2 cases in which aneurysmal dilatation of the aorta was found at autopsy. The same year Etter and Glover6