RT Journal
A1 MOEHLIG RC
T1 THe pituitary gland and the suprarenal cortex
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1929
FD September 1
VO 44
IS 3
SP 339
OP 343
DO 10.1001/archinte.1929.00140030038003
UL http://dx.doi.org/10.1001/archinte.1929.00140030038003
AB The pituitary gland is functionally related to the suprarenal cortex, and this relationship can be understood from embryologic considerations. There can be no question but that glandular interrelationships have made it difficult to understand many problems in endocrinology. As Hoskins1 has shown, there are almost innumerable combinations possible between the endocrine glands. It is, therefore, with some hesitancy that a discussion is undertaken to point out a particular correlation. The explanation to be offered finds its strength in its agreement with the known clinical, pathologic and experimental facts, and is based on sound fundamentals of embryology.Aplastic states of the pituitary gland are concomitant with aplasia of the suprarenal cortex and, conversely, hyperplasia of the pituitary gland results in hyperplasia of the suprarenal cortex.From the clinical side, the best examples of the aplastic and deformed pituitary are found in anencephalic fetuses. Hemicephaly, oxycephaly and other developmental defects are accompanied