RT Journal
A1 CECIL RL, NICHOLLS EE, STAINSBY WJ
T1 THe bacteriology of the blood and joints in chronic infectious arthritis
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1929
FD May 1
VO 43
IS 5
SP 571
OP 605
DO 10.1001/archinte.1929.00130280002001
UL http://dx.doi.org/10.1001/archinte.1929.00130280002001
AB This study deals with the etiology of a form of chronic arthritis which has been variously referred to as rheumatoid arthritis, arthritis deformans or chronic infectious arthritis. Goldthwaite1 and his school call it atrophic arthritis. It may be defined as a chronic inflammatory condition of the joints and periarticular tissues, characterized in the earlier stages by migratory swelling and stiffness of the joints, and in the later stages by more or less deformity and ankylosis. In the great majority of cases, several joints are involved; indeed, one of the most striking features of the disease is its tendency, if unchecked, to progress and finally to involve nearly every joint in the body.The etiology of chronic deforming arthritis has long been a subject for debate. Perhaps no disease in the whole realm of internal medicine has been more prolific of hypotheses and theories. It has long been recognized that there