RT Journal
A1 BARGEN J, JACOBS MF
T1 PErforations of the colon in chronic ulcerative colitis
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1929
FD April 1
VO 43
IS 4
SP 483
OP 487
DO 10.1001/archinte.1929.00130270057004
UL http://dx.doi.org/10.1001/archinte.1929.00130270057004
AB The complications and sequelae of chronic ulcerative colitis place it in the category of serious diseases. Chronic ulcerative colitis means a definite disease entity presenting characteristic clinical, proctologic, roentgenologic and pathologic observations. Clinically, it is characterized by exacerbations and remissions, and occasionally by acute fulminating infection. During the active stage of the disease, foul-smelling mucus, pus and blood are discharged from the rectum, often associated with almost intractable diarrhea. The latter depends on the extent of involvement of the colon and the severity of the infections so that the patient may complain of constipation associated with frequent passages of blood and pus, particularly if the lesions involve only the rectum and the rectosigmoid.Thus, because of few pathognomonic symptoms of chronic ulcerative colitis the disease may be confused with amebiasis, tuberculosis, a malignant condition, typhoid fever and other lesions of the colon. According to Buie,1 however, the disease presents a