RT Journal
A1 KELMAN SR
T1 EXperimental emphysema
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1919
FD September 1
VO 24
IS 3
SP 332
OP 346
DO 10.1001/archinte.1919.00090260087007
UL http://dx.doi.org/10.1001/archinte.1919.00090260087007
AB In the recent epidemic of influenza and bronchopneumonia, among the S. A. T. C. at the Iowa State University, there were about 1,100 cases with thirty-three fatalities. Of these, twenty came to necropsy.One of the most striking and constantly present postmortem findings in these cases was a marked vesicular and interstitial emphysema. The vesicular emphysema was mainly marginal, but large emphysematous bullae were quite frequently observed subpleurally. The apices of both lungs, especially the upper lobes, were involved. In many cases superficial distended air vesicles ruptured and allowed an escape of air subpleurally, giving the lung a beaded appearance. The roots of the lungs were also quite commonly involved.The interstitial emphysema involved mainly the anterior and posterior mediastinum, the layers of the pericardium and pericardial fat, the retroperitoneal and especially the perirenal tissues. The absence of inflammation and our inability to find organisms in stained preparations of these