RT Journal
A1 Schattner A
T1 TO e or not to e
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1999
FD November 8
VO 159
IS 20
SP 2485
OP 2485
DO 
UL http://dx.doi.org/
AB 
Vitamin E has antioxidant activity that inhibits subendothelial low-density lipoprotein oxidation and atherosclerotic plaque formation.1 Nevertheless, current opinion does not advocate the use of daily vitamin E supplementation to reduce the risk of vascular events2 and the skepticism concerning the use of vitamin E as an adjunctive treatment for either secondary or primary prevention of vascular events is based on the present "lack of solid evidence of efficacy."2 However, a careful overview of the data allows for an alternative approach, which is based on several considerations.