RT Journal A1 Rugge M, Cassaro M, Leo G, Farinati F, Graham DY T1 Helicobacter pylori and gastric cancer: Both primary and secondary preventive measures are required JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1999 FD November 8 VO 159 IS 20 SP 2483 OP 2484 DO UL http://dx.doi.org/ AB We read with interest the article by Fendrik et al1 in the January issue of the ARCHIVES. The authors evaluated the cost-effectiveness of primary prevention of gastric cancer based on the eradication of the Helicobacter pylori infection in different epidemiological contexts and using different strategies. Both single H pylori serological testing and H pylori testing followed by confirmatory tests resulted in a positive cost-effective balance, proportional to the cancer risk associated with the considered population.