RT Journal A1 Mann SJ T1 MUtual influences between paroxysmal hypertension and psychiatric disturbance JF Archives of Internal Medicine JO Archives of Internal Medicine YR 1999 FD September 27 VO 159 IS 17 SP 2091 OP 2092 DO UL http://dx.doi.org/ AB Dr Boylan describes a woman with dysautonomia and paroxsmal depression, with the latter responding to an antidepressant. Of interest, the patient's episodes of depression were not accompanied by blood pressure spikes. This may represent the flip side of my observations in terms of the reciprocal nature of affective and autonomic manifestations. In Dr Boylan's case, the affective manifestation dominated, and autonomic manifestation was absent. In my cases of paroxysmal hypertension, the autonomic manifestation dominated, with a striking absence of affective manifestation. In both circumstances, severely distressful emotions, which threatened to overcome psychological defenses against awareness, were at play. And in both, antidepressant agents provided a very effective intervention.