RT Journal
A1 Fugh-Berman A
T1 Herbal medicinals: Selected clinical considerations, focusing on known or potential drug-herb interactions
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1999
FD September 13
VO 159
IS 16
SP 1954
OP 1954
DO 
UL http://dx.doi.org/
AB 
The unreferenced statement that ginkgo should be avoided in patients with epilepsy is not substantiated. The statement that ginkgo toxin is found in both leaf and seed is true but misleading. Ginkgo seeds, which are eaten on special occasions in Asia, contain 4‘-O-methylpyridoxine, an anti–vitamin B6 neurotoxin. Boiling inactivates 99% of this toxin. However, during food shortages in China and Japan, overconsumption of ginkgo seeds resulted in a syndrome called gin-nan sitotoxism, with a 27% mortality rate.2