RT Journal
A1 De Lorenzo F, Kakkar VV
T1 MIght cold adaptation reduce cardiovascular mortality during winter?
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1999
FD September 13
VO 159
IS 16
SP 1954
OP 1954
DO 
UL http://dx.doi.org/
AB 
The mechanisms by which abrupt rupture of atherosclerotic plaques occur during cold exposure have been associated with an increased sympathetic activity that causes increased blood pressure, heart rate, and cardiac workload.2 In addition, increased serum lipids levels,3 plasma viscosity,4 fibrinogen values,3,5 factor VII:c levels,5 and platelet counts have been reported.4 Therefore, several authors have concluded that the effect of cold weather during winter on cardiovascular mortality was mediated by the increase of these risk factors.3- 5