RT Journal
A1 Tuldrà A, Ferrer M, Fumaz CR, et al
T1 MOnitoring adherence to hiv therapy
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1999
FD June 28
VO 159
IS 12
SP 1376
OP 1377
DO 
UL http://dx.doi.org/
AB 
We designed a cross-sectional study to detect key variables in adherence to HAART. One hundred unselected patients with HIV in a general hospital during April 1998 were interviewed by a psychologist trained in adherence. They were asked about the number of pills skipped during the last month. Patients were also asked about variables related to adherence (Table 1) and completed the Profile of Mood States questionnaire.2 The percentage of adherence was calculated with the following formula: (number of pills taken/number of pills prescribed)×100. To test the veracity of the self-reported information, blood samples of 25 randomly selected patients were obtained and drug levels of protease inhibitors were determined by high-performance liquid chromatography.3 We compared the adherence-related data by assessing the percentage of patients with a rate of compliance higher than 95% ( Table 1).