RT Journal
A1 Lesho EP, Hyder A
T1 PRevalence of subtle cobalamin deficiency
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1999
FD February 22
VO 159
IS 4
SP 407
OP 407
DO 
UL http://dx.doi.org/
AB 
The prevalence of cobalamin deficiency has ranged from 3% to 29%.1- 3 Subtle cobalamin deficiency is defined as metabolic evidence of cobalamin deficiency, such as elevated serum or urine methylmalonate levels, or abnormal findings on a deoxyuridine suppression test, or the absence of neurological symptoms or megaloblastic anemia.4 The prevalence of subtle cobalamin deficiency is unknown, but in one elderly population was 39%.1 Concerns have been raised regarding the initiation of widespread folate supplementation because it might obscure the hematologic effects of cobalamin deficiency and facilitate the progression of neuropsychiatric damage.4- 5