RT Journal
A1 Tsuji H
T1 LOw serum cholesterol level and increased ischemic stroke mortality
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2011
FD June 27
VO 171
IS 12
SP 1116
OP 1130
DO 10.1001/archinternmed.2011.255
UL http://dx.doi.org/10.1001/archinternmed.2011.255
AB 
Different from coronary disease, which mostly results from coronary atherosclerosis with superimposed coronary thrombosis, stroke includes various pathological entities. Stroke includes not only ischemic and hemorrhagic stroke but also subtypes of ischemic stroke. The stroke-lipid connection would depend on the types and the subtypes of stroke. Reductions of stroke by cholesterol-lowering therapy have been documented in patients with previous stroke and those at high risk for coronary disease. However, these results seem to be based on predominance of atherothrombotic stroke over other subtypes of ischemic stroke in the study population, which shares a similar etiology with coronary disease.1- 2