RT Journal A1 Hansen M, Gislason G, Torp-Pedersen C T1 DUal antiplatelet therapy and the risk of bleeding—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD April 25 VO 171 IS 8 SP 782 OP 790 DO 10.1001/archinternmed.2011.148 UL http://dx.doi.org/10.1001/archinternmed.2011.148 AB First, dual aspirin and clopidogrel should not be a treatment regime on patients who do not receive OAC therapy due to bleeding risk. The bleeding risk with dual aspirin and clopidogrel therapy is at best comparable to what is seen with OAC therapy. This was shown in the ACTIVE W trial, which also taught us that to obtain protection against stroke, you need OAC therapy.2