RT Journal
A1 Lin H
T1 HIgh or low doses of ppis for patients with peptic ulcer bleeding?
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2010
FD October 11
VO 170
IS 18
SP 1699
OP 1700
DO 10.1001/archinternmed.2010.353
UL http://dx.doi.org/10.1001/archinternmed.2010.353
AB 
However, these results are different from the international consensus and previous observation of mine and my colleagues. Several points require further clarification. First, endoscopic hemostatic therapy is not indicated for patients with low-risk stigmata (eg, a clean-based ulcer or a nonprotuberant pigmented dot in an ulcer base) who have a low rebleeding rate.2- 3 Unfortunately, Wang et al1 have cited some studies that included low-risk patients: Yilmaz et al4 included 190 patients with low-risk stigmata (clean base, n = 144; flat pigmented spots, n = 46), while Bajaj et al5 included 11 patients (44%) with low-risk stigmata. In these low-risk patients, rebleeding rates may be similar with either high or low doses of PPIs. Therefore, the conclusion of Wang et al1 may be misleading.