RT Journal
A1 Tritos NA, Hartzband P
T1 RApid improvement of osteoporosis following parathyroidectomy in a premenopausal woman with acute primary hyperparathyroidism
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 1999
FD July 12
VO 159
IS 13
SP 1495
OP 1498
DO 10.1001/archinte.159.13.1495
UL http://dx.doi.org/10.1001/archinte.159.13.1495
AB We describe a premenopausal white woman with symptomatic acute primary hyperparathyroidism and marked osteoporosis. After undergoing a parathyroidectomy, the patient experienced not only rapid symptomatic relief, but also marked improvement in bone mineral density, which increased by 25% in the hip and by 22% in the lumbar spine 1 year after the surgery. Acute primary hyperparathyroidism should be considered in any patient with severe symptomatic hypercalcemia. Appropriate treatment with early parathyroidectomy can result in significant and rapid improvement in bone mineral density.