RT Journal A1 Pantanowitz L, Bower M, Krown SE, Stebbing J T1 HIv infection and esophageal cancer—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2010 FD May 24 VO 170 IS 10 SP 916 OP 917 DO 10.1001/archinternmed.2010.114 UL http://dx.doi.org/10.1001/archinternmed.2010.114 AB We thank Dr Rastegar for sharing this interesting case. Some cases of esophageal cancer in HIV-infected individuals may well be linked to HPV infection. We observed 1 HIV-infected individual who had an HPV-related condyloma of his esophagus (Figure), who was not included in our published series because we only included cases of invasive esophageal carcinoma. Others have reported similar individuals with HPV-related esophagitis.1 Recent published data support an association between high-risk HPV and esophageal carcinomas,2- 3 although causation is not established and is controversial.