RT Journal A1 Havas S T1 Treatment of type 2 diabetes: One extreme to another—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2009 FD July 13 VO 169 IS 13 SP 1241 OP 1247 DO 10.1001/archinternmed.2009.187 UL http://dx.doi.org/10.1001/archinternmed.2009.187 AB Dr Hirsch raises important points. Pharmaceutical companies and the American Diabetes Association (ADA) continue to promote using glucose level–lowering drugs in type 2 diabetes mellitus to attain an HbA1c level below 7% despite recurring evidence of potential harm and scant evidence of benefit. Both influenced the National Committee on Quality Assurance (NCQA) to approve a performance measure for that level.1 Yet randomized clinical trials (RCTs) have not demonstrated significant benefits from glucose level–lowering agents in type 2 diabetes except for metformin. Therefore, it makes no sense for third-party payers to hold practitioners to a non–evidence-based measure of an HbA1c level below 7%.